Total synthesis of psammaplysenes A and B, naturally occurring inhibitors of FOXO1a nuclear export
AuthorGeorgiades, Savvas N.
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(Chemical Equation Presented) Two inhibitors of FOXO1a-mediated nuclear export, psammaplysenes A and B, have been synthesized by a flexible and efficient route. A common starting material, 4-iodophenol, was used to prepare both halves of these pseudosymmetric dibromotyrosine-derived metabolites. © 2005 American Chemical Society.