Total synthesis of psammaplysenes A and B, naturally occurring inhibitors of FOXO1a nuclear export

Georgiades, Savvas N.; Clardy, J.

doi:10.1021/ol0513286

dc.contributor.author	Georgiades, Savvas N.	en
dc.contributor.author	Clardy, J.	en
dc.creator	Georgiades, Savvas N.	en
dc.creator	Clardy, J.	en
dc.date.accessioned	2019-11-21T06:19:06Z
dc.date.available	2019-11-21T06:19:06Z
dc.date.issued	2005
dc.identifier.issn	1523-7060
dc.identifier.uri	http://gnosis.library.ucy.ac.cy/handle/7/55494
dc.description.abstract	(Chemical Equation Presented) Two inhibitors of FOXO1a-mediated nuclear export, psammaplysenes A and B, have been synthesized by a flexible and efficient route. A common starting material, 4-iodophenol, was used to prepare both halves of these pseudosymmetric dibromotyrosine-derived metabolites. © 2005 American Chemical Society.	en
dc.source	Organic letters	en
dc.source.uri	https://www.scopus.com/inward/record.uri?eid=2-s2.0-25444454350&doi=10.1021%2fol0513286&partnerID=40&md5=43c089e5515cb82e2249e7a4337a626f
dc.subject	article	en
dc.subject	drug derivative	en
dc.subject	metabolism	en
dc.subject	chemistry	en
dc.subject	drug antagonism	en
dc.subject	synthesis	en
dc.subject	chemical structure	en
dc.subject	Molecular Structure	en
dc.subject	forkhead transcription factor	en
dc.subject	Forkhead Transcription Factors	en
dc.subject	tyrosine	en
dc.subject	Active Transport, Cell Nucleus	en
dc.subject	psammaplysene A	en
dc.subject	psammaplysenes B	en
dc.subject	active transport	en
dc.title	Total synthesis of psammaplysenes A and B, naturally occurring inhibitors of FOXO1a nuclear export	en
dc.type	info:eu-repo/semantics/article
dc.identifier.doi	10.1021/ol0513286
dc.description.volume	7
dc.description.issue	19
dc.description.startingpage	4091
dc.description.endingpage	4094
dc.author.faculty	002 Σχολή Θετικών και Εφαρμοσμένων Επιστημών / Faculty of Pure and Applied Sciences
dc.author.department	Τμήμα Χημείας / Department of Chemistry
dc.type.uhtype	Article	en
dc.description.notes	<p>Cited By :21</p>	en
dc.source.abbreviation	Org.Lett.	en
dc.contributor.orcid	Georgiades, Savvas N. [0000-0002-6106-9904]
dc.gnosis.orcid	0000-0002-6106-9904

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